July 9, 2018
NRG Oncology Broadcast archives are accessible from our website at any time. Please bookmark  this link  for your convenience.



The NRG Oncology Semiannual Meeting is this week, July 12-14, 2018 in Philadelphia! Read more.

The NRG Oncology publications page on the website has moved. Read more
NRG Oncology Semiannual Meeting

Pre-Registration is now Closed!
We hope you can join us for the NRG Oncology Semiannual Meeting, July 12-14, 2018, at the Philadelphia Marriott Downtown in Philadelphia, PA. Please register onsite at the meeting. More information is available on the NRG Oncology website.

Meeting Highlights

  • Summer Symposium: Thursday, July 12 - 8am-3pm in Salon F Read more
  • Digital Health and Personal Connected Health MinisymposiumThursday, July 12 - 1-3pm in Salon CD  Read more
  • Health Disparities Workshop Special Session: Intervening on the Financial Toxicity of Cancer Care - Friday, July 13 - 7-9am in Salon H Read more
  • Scientific Session: Friday, July 13 - 8-10am in Salon EF Read more
  • Social Media Workshop: Friday, July 13 - 10-11:30am in Franklin 13 *New Session! Read more
  • Workshops! Plan to Attend! details posted to the NRG Oncology meeting page: NRG-GI002 and GI004; NRG-BR005; NRG-BR003/NSABP B-55/NRG-BR004; and Audit Training
  • NRG-LU003 Kick Off Meeting: Friday, July 13 - 11:30am-1pm in Franklin 13 Read more
  • NRG-GU006 Training Session: Friday, July 13 – 12-1pm in Room 408-409 Read more

CCD 800-line Coverage during the Meeting
Information regarding the availability of the NRG Oncology-Pittsburgh Center Clinical Coordinating Department (CCD) during the NRG Oncology meeting is posted to the NRG Oncology  meeting page and the CTSU website.

CTN/CRA Educational Programs Thursday, July 12, 2018
Slide sets for the PSC Clinical Trials Nurse/Clinical Research Associate Workshop and Educational Lunch are posted to Nurses and CRA /Education and Training on the NRG Oncology website.(A password is required). A listing of the Roundtable topics, with a room map, and the Roundtable handouts are posted there as well. If you plan to attend these sessions, please download the slides and handouts prior to the meeting and bring them with you. No handouts will be provided at the meeting. Also, please check the NRG Oncology website frequently prior to the meeting, as additional presentations and handouts may be added.


CLOSURES AND SUSPENSIONS
GENITOURINARY
NRG-GU003: Study Closure Memorandum dated July 9, 2018 (posted to CTSU)

OTHER PROTOCOL NOTICES
1. AE REPORTING
*Reminder* - The Routine AE Reporting Guidance Document can now be found on the NRG Oncology website.

2. BREAST
NSABP B-55/BIG 6-13: OlympiA Newsletter, 19th Issue (posted to CTSU)

3. VTOC Training
The VTOC Webinar Training Series schedule and registration is available for NRG Oncology Research Associates working on RTOG 0924, RTOG 0920, NRG-HN001, NRG-HN002, NRG-CC003, and NRG-CC004. Space is limited so register now and reserve your seat.  The next webinar training is scheduled for August 15, 2018.

 

DRUG SAFETY UPDATES
Safety updates have been issued for the following studies:

DRUG NAME 

PROTOCOL                      

WEBSITE FOR SAFETY REPORTS

Ipilimumab

NRG-BN002
NRG-GY003  

NRG

Nivolumab

 

NRG-BN002
NRG-GY002
NRG-GY003

NRG
NRG
NRG

Pembrolizumab

NRG-HN003

NRG

Selumetinib

GOG-0239

NRG



MGMT
Promoter Methylation Associated with Improved Survival for Patients with WHO Grade II Gliomas
Further exploration into the endpoints of the NRG Oncology/RTOG 0424 trial resulted in the discovery that  MGMT promoter methylation is an independent prognostic biomarker of high-risk, low-grade glioma treated with temozolomide and radiation. This is the first study of its kind to validate the prognostic significance of  MGMT promoter methylation in this patient population and treatment regimen Read the full press release here.
 


Stereotactic Body Radiation Therapy (SBRT) May be an Effective and Safe Alternative for Patients with Medically Operable Early-Stage Lung Cancer

JAMA Oncology recently published data from NRG Oncology’s RTOG 0618 trial [clinicaltrials.gov identifier NCT00551369], which shows that the utilization of Stereotactic Body Radiation Therapy (SBRT) as a treatment for medically operable lung cancer is associated with favorable primary tumor control and local control rates. Read the full press release here.

NEW LOCATION ON WEBSITE
Please note that the NRG Oncology Publications tab on the website has relocated. You can now find the publications section under the Clinical Trials tab of the website:  nrgoncology.org/Clinical-Trials/Publications

NRG Oncology is pleased to report the scientific articles and abstracts that have appeared or have been presented during the previous week. This publications report includes links, when available, to the article, PubMed abstract, or association abstract.

JOURNAL ARTICLES
Francis PA, Pagani O, Fleming GF, Walley BA, Colleoni M, Láng I, Gómez HL, Tondini C, Ciruelos E, Burstein HJ, Bonnefoi HR, Bellet M, Martino S, Geyer CE Jr, Goetz MP, Stearns V, Pinotti G, Puglisi F, Spazzapan S, Climent MA, Pavesi L, Ruhstaller T, Davidson NE, Coleman R, Debled M, Buchholz S, Ingle JN, Winer EP, Maibach R, Rabaglio-Poretti M, Ruepp B, Di Leo A, Coates AS, Gelber RD, Goldhirsch A, Regan MM; SOFT and TEXT Investigators and the International Breast Cancer Study Group. Tailoring Adjuvant Endocrine Therapy for Premenopausal Breast Cancer.  N Engl J Med. 2018 Jun 4. doi: 10.1056/NEJMoa1803164. [Epub ahead of print] PubMed PMID: 29863451.Read more

PUBLICATIONS REMINDERS
Please note the following upcoming meeting and abstract submission deadline dates

Upcoming Meetings
American Association of Physicists in Medicine (AAPM); Jul 29-Aug 2, 2018; Nashville, TN

ASCO Research Community Forum Annual Meeting; Sep 23-24, 2018; Washington, DC

College of American Pathologists (CAP); Oct 20-24, Chicago, IL

European Society for Medical Oncology (ESMO); Oct 19-23, 2018; Munich, Germany

Upcoming Abstract Submission Deadlines
American Society for Radiation Oncology (ASTRO); Oct 21-24, 2018; San Antonio, TX; Late-breaking submission site opens Jul 18, 2018; Late-breaking submission site closes Aug 1, 2018

European Society for Medical Oncology (ESMO); Oct 19-23, 2018; Munich, Germany; Late-breaking Sep 17, 2018

Society of Clinical Research (SOCRA); Sep 28-30, 2018; New Orleans, LA; meeting abstracts submission deadline July 20, 2018

 

NRG Oncology is proud to be an active participant of #CancerMoonShot.
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